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Progesterone and pregnancy rate
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Progesterone and pregnancy rate

14 August 2011
|In FAQ
|By Gülden Halis

August 14, 2011

The influence of progesterone on the pregnancy rate

A recently published study examined whether the progesterone level measured on the day of ovulation provides a prediction of the expected pregnancy rate.

Several studies had suggested this.

It could clearly be shown that, if the progesterone level on the „trigger day“ is above 1.5 ng/ml, the pregnancy rate is significantly reduced. The study design allowed to attribute this to the progesterone-induced maturation of the uterine lining and not to a reduction in the quality of the eggs.

The authors recommend freezing all cells and embryo transfer in a subsequent natural cycle in the event of a progesterone increase.

Sources:
A. Pellicier, E. Labarta et al.- Endometrial receptivity is affected in women with high circulating progesterone levels at the end of the follicular phase: a functional genomics analysis in Human Reproduction, Vol. 26, No. 7, July 2011

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