Mini-IVF™

Many women for whom treatment IVF is to be carried out are afraid of the need for daily injections and the high drug costs that come with it.

Other points of concern are the risk of multiple births, the resulting premature birth, and the so-called overstimulation syndrome (OHSS).

The Mini IVF™ procedure is a completely new approach in this field, which was initially developed by Prof. Kato in Japan and further refined by other pioneers IVF such as Dr. John Zhang of the New Hope Fertility Center - New York.

With the Mini IVF™ it is possible to avoid the development of overstimulation syndrome by 99%, and only very few (3-4) injections are required. Where conventional IVF treatment costs 1200-2000 euros, here the cost is expected to be a maximum of 380-400 euros. In addition, the stimulation procedure is very simple. Unlike conventional stimulation, the patient does not have to be in a hospital bed during the procedure. conventional IVF, In the mini IVF™ procedure, which usually involves the collection of 15-20 eggs, only 4-5 of these are actually of high quality (depending on age). In the mini™ procedure, however, only 4-8 eggs are expected to mature. The remarkable thing is that here too, 3-5 eggs of high quality mature. In essence, despite the reduction in the number of eggs, the proportion of eggs of the highest quality remains unchanged.

The so-called „artificial menopause injection“ or „down regulation“ is also not necessary in this case. Premature ovulation rarely occurs with the Mini IVF™ system.

The side effects in women, such as mild headaches and/or fatigue, usually last only a few days.

Today we know that the extremely high stimulation dose used in conventional IVF IVF seems to lead to a deterioration in the implantation rate after embryo transfer. Now one might think that this problem would be solved by using less stimulation. But unfortunately, the tablets used in Mini IVF™ lead to a poor development of the endometrium in some women. This means that on the one hand, with fewer drugs, a similar number of good eggs are obtained, but at the same time – possibly – the pregnancy rate is reduced due to a poor endometrium. The solution to the problem lies in Cryoconservation the eggs or the fertilized eggs. Since this cryopreservation is performed by vitrification, one can assume a survival rate of the cells of 95-98%.

Therefore, it is recommended to culture the eggs obtained, freeze the embryos, and only transfer them in the next cycle (Kryo-Transfer).

In addition, we recommend the so-called „SET“ (Single Embryo Transfer) procedure. Blastocystic pregnancy, Thus, pregnancy rates that are expected in a cycle of conventional IVF IVF with the transfer of 2 embryos are obtained without having to take into account the 20 percent risk of a twin pregnancy.

Which women are suitable for performing the Mini IVF™ / ICSI?

• Women who do not want conventional treatment IVF with associated high-dose stimulation therapy

• Women who want to benefit from multiple, simultaneously obtained eggs due to the implantation of eggs or (pre-)fertilized eggs (i.e., also for the so-called „social freezing“)

• Women who are undergoing cancer treatment and wish to freeze their eggs (WITHOUT A PARTNER) or (PRE-)fertilized eggs (WITH A PARTNER)

• Women who have had bad experiences with hormonal stimulation

• Women at high risk of overstimulation syndrome (OHSS)

• the so-called „low-responders“, i.e. women who respond poorly to hormonal stimulation, who have a low ovarian reserve (premature menopause, women in their mid-40s)

• Older women, who in any case, despite hormonal stimulation often produce only 1-3 eggs

This procedure is not recommended as the primary therapy. It should first be performed with conventional IVF stimulation! It is also not a method of cost savings, as the costs of cryopreservation and the subsequent cryocycle ultimately do not come at a lower cost.