Blastocyst culture

Whether it's after IVF or IVF/ICSI, Or, alternatively, in the so-called „Cryo cycle“Embryos can be cultured for 2 to 3 or even up to the 5th day. This is also possible in Germany, with its strict embryo protection law, and is also carried out with great success by some centers. However, the problem in Germany is that already on the 1st day of culture, those cells must be selected that are to be transferred, which is usually 2-3 embryos per cycle (see). IVF RegisterHowever, not even every „top-quality embryo“ reaches this stage, as the conditions in the incubator are not as optimal as those in the uterus. It must be assumed that only 25-50% of the „day 2 embryos“ will develop into a blastocyst.

The main advantage of the 5-day culture can actually only be profited from if it is possible to select from all (that is, more than 2-3) embryos. Therefore, apart from exceptions, it makes little sense in Germany to perform blastocyst culture; indeed, a potentially possible pregnancy might not even be possible as a result.

Under the conditions of the German Embryo Protection Act, it is better to perform the embryo transfer on the 2nd or 3rd day of pregnancy.

Bastion culture — Sequence of an embryo hatching in the 5th image

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Monitoring / VZO (intercourse to the optimum)

Depending on the couple's wishes, the present findings and other basic requirements (age, duration of the unmet desire for a child, etc.) may indicate that it is advisable to first monitor the course of the natural cycle through more intensive examinations (hormone levels; ultrasound). As a result, you can be informed about the optimal time for conception (the best time to achieve pregnancy).

Hormone treatment

If the hormone test performed at the beginning (if necessary after further evaluation) revealed a significant hormone disorder, this can be treated specifically. Of course, various hormone disorders can also occur simultaneously, so that several medications may occasionally have to be taken in parallel.

Anaesthesia

Anaesthesia

General anesthesia puts you into a sleep-like state; that is, it shuts down your consciousness and, above all, your sense of pain.

IUI

Insemination is one of the relatively simple procedures and is performed in cases of relatively mild male fertility problems or disorders in the cervical canal, e.g., disorders of mucus production or after a conectomy (incision of the external opening of the vagina). The treatment can be performed with or without hormone treatment depending on any pre-existing oocyte maturation disorder. The purpose of this treatment is to bring the prepared sperm in high concentration close to the egg cell in order to promote the occurrence of fertilization.

IVF

IVF (Reagent glass insemination) is typically used when the woman has bilateral fallopian tube blockage. But the man’s reduced sperm quality, the woman’s age, the couple’s distress, and the failure of other treatments can also lead to the decision to IVF seek this treatment.

ICSI

In cases of severely impaired sperm quality, or when only sperm can be obtained via testicular tissue sampling, an additional test is ICSI required.

Cryoconservation

Thus, if IVF or IVF + ICSI „excessive“ (partially fertilized) eggs have been frozen, they can be used in the so-called „cryocycle“.

ADI

If no sperm are present at all, the use of donor sperm can also be considered. Other reasons may also seem reasonable.

Blastocyst culture

In blastocyst culture, the embryos are further cultured until the 5th day.