{"id":5211,"date":"2010-10-19T09:39:54","date_gmt":"2010-10-19T07:39:54","guid":{"rendered":"https:\/\/www.kinderwunschteam.berlin\/?p=5211"},"modified":"2026-04-23T14:26:10","modified_gmt":"2026-04-23T12:26:10","slug":"single-versus-double-intrauterine-insemination","status":"publish","type":"post","link":"https:\/\/kwt.meiio.net\/en\/faq-en\/single-versus-double-intrauterine-insemination","title":{"rendered":"Single versus double intrauterine insemination"},"content":{"rendered":"

Comparison of the effectiveness of single versus double intrauterine insemination with three different timing regimens<\/h2>\n

By Dr. Esra Tonguc et al<\/strong><\/p>\n

Objective<\/h3>\n

To compare double insemination with two different single insemination regimens.<\/p>\n

Patient(s)<\/h3>\n

Four hundred and fifty patients with unexplained infertility, male factor, and ovulatory dysfunction underwent controlled ovarian hyperstimulation with gonadotropin.<\/p>\n

Intervention(s)<\/h3>\n

The patients were divided randomly into three groups: patients in group 1 underwent a single preovulatory intrauterine insemination (IUI) performed 24 hours after hCG administration. Patients in group 2 underwent two IUIs performed 12 and 36 hours after hCG administration. Patients in group 3 underwent a single periovulatory IUI performed 36 hours after hCG administration.<\/p>\n

Result(s)<\/h3>\n

The total pregnancy rate per patient was 14.2 % (64 pregnancies in 450 patients). Group 1 had 17 pregnancies (11.3%), while groups 2 and 3 had 21 (14.0%) and 26 (17.2%) pregnancies, respectively. The difference between the three groups in regard to pregnancy rates was statistically not significant.<\/p>\n

Conclusion(s)<\/h3>\n

Despite the 36th hour being the preferred timing for IUI, there was no difference regarding pregnancy rates between single 24th hour and double 12th- and 36th-hour inseminations. This finding suggests that the 24th-hour IUI might be preferred in demanding situations.<\/p>\n

Source:<\/span>
\nFrom Fertility\/ Sterility Volume 94<\/strong><\/a>, Issue 4<\/strong><\/a>, Pages 1267-1270 (September 2010)<\/p>\n","protected":false},"excerpt":{"rendered":"

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